PP19 - EFFECTS ON THE MARITAL QUALITIES, PSYCHOLOGY AND QUALITY OF LIFE AMONG MARRIED WOMEN WITH FUNCTIONAL DYSPEPSIA, IRRITABLE BOWEL SYNDROME AND OVERLAP OF BOTH DISORDERS Poster #22

NH Hamid 1,4, N Mahd-Ablah1, 3, NM Nor1, PO Tan1, KK Zulkifli1,2, SR Hassim1,3, SN Muhamad1, A Abdul Aziz1, N Mustaffa4, R Muhamad4, Z Zahari5 ,Y.C. Kueh3, YY Lee1,4

1 GI Function & Motility Unit, Hospital Universiti Sains Malaysia, Kota Bharu, Malaysia.
2 Faculty of Medicine, Universiti Teknologi Mara, Sungai Buloh, Malaysia
3 Unit of Biostatistics and Research Methodology, School of Medical Sciences, Universiti Sains Malaysia, Kota Bharu, Malaysia.
4School of Medical Sciences, Universiti Sains Malaysia, Kota Bharu, Malaysia.
5Faculty of Pharmacy, Universiti Sultan Zainal Abidin (UniSZA), Besut Campus, Terengganu, Malaysia.

Objective(s):
Functional gastrointestinal disorders (FGIDs) including functional dyspepsia (FD) and irritable bowel syndrome (IBS) are associated with worse psychology outcomes, quality of life (QOL), and possibly marriage relationships too. Our study was aimed to determine if poor marital quality may affect well-being and QOL of FGIDs among women.

Methodology:
This was a cross-sectional study involving married Malay women aged ≥18 years with FGIDs diagnosed based on the Rome IV criteria. Eligible women were asked to complete a survey booklet consisting of 154 items included demographics, revised dyadic adjustment scale (RDAS), relationship dynamic scale (RDS), Hospital Anxiety Depression Scale (HADS), Coping Strategies Scale (CSS), Multidimensional Pain Inventory (MPI) and EQ-5D-5L. Multinomial logistic regression was used to determine association.

Results:
Of 1130 screened, 514 were included for analysis, with a response rate of 45.4%. Prevalence of overlap FD-IBS was 36.6%, FD was 34.0%, and IBS was 29.4%. Married women with IBS vs. FD reported 5 times better values (p<0.001) but 90% less affection (p=0.005) based on RDAS and 40% more conflicts (p=0.002) based on RDS. Women with IBS vs. FD were also 1.4 times more likely to have catastrophizing (p=0.001) and negative responses (p<0.001) but less depressed (p=0.007). For QOL measured using EQ-5D-5L, those with IBS vs. FD reported 10% lower EQVAS (p=0.01), almost 6 times worse mobility (p=0.001) and 5 times more pain/discomfort (p=0.04). Women with IBS vs. overlap reported 30% more affection (p=0.04) and 40% less pain or discomfort (p=0.04) but twice the risk of poor mobility (p=0.01).

Discussion and Conclusions:
Different domains of marital relations were affected differently in FD, IBS and or overlap disorder in married Malay women. Affected individuals have worst catastrophizing, more negative responses and worse QOL.